STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZMIZ1-2SP-RING-type domain-containing protein. (1009 aa)    
Predicted Functional Partners:
KCTD2
BTB/POZ domain-containing protein KCTD2.
    
 0.820
SUMO1
Small ubiquitin-related modifier.
    
 0.756
NFATC2IP
NFATC2-interacting protein.
   
 0.721
SUMO3
Small ubiquitin-related modifier.
    
 0.715
BIRC6
Baculoviral IAP repeat-containing protein 6 isoform A.
    
 0.609
BARD1
BRCA1-associated RING domain protein 1 isoform B.
    
 0.602
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.586
TP53BP1-1
Tumor suppressor p53-binding protein 1 isoform A.
    
 0.524
NSMCE2
E3 SUMO-protein ligase NSE2.
    
 
 0.513
RAD18
E3 ubiquitin-protein ligase RAD18.
   
 
 0.501
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.