STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPG5Ectopic P granules 5-like protein. (2585 aa)    
Predicted Functional Partners:
ATG2B
Autophagy-related 2-like protein B isoform A.
   
  
 0.789
TECPR2
Tectonin beta-propeller repeat-containing protein 2.
   
  
 0.761
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
      
 0.755
WIPI2
WD repeat domain phosphoinositide-interacting protein 2 isoform B.
      
 0.685
ATG4B
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
      
 0.638
SNAP29
Synaptosomal-associated protein 29.
      
 0.616
ULK2
Serine/threonine-protein kinase ULK2.
      
 0.613
EI24
Etoposide-induced 2.4-like protein.
      
 0.612
PSTPIP2
Proline-serine-threonine phosphatase-interacting protein 2.
 
    
 0.611
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
      
 0.609
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.