STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEDD4L-2Uncharacterized protein. (1002 aa)    
Predicted Functional Partners:
DLG3
Uncharacterized protein; Belongs to the MAGUK family.
    
  0.909
NEDD4L
E3 ubiquitin-protein ligase.
  
  
 
0.901
SMAD7
Mothers against decapentaplegic homolog.
    
 0.884
SCNN1B
Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
    
 0.863
SMAD2-2
Mothers against decapentaplegic homolog.
    
 0.845
EGFR
Uncharacterized protein.
    
 0.789
CDC34
Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.774
RPS27A
Ubiquitin-40S ribosomal protein S27a.
    
 0.768
SCARB1
Scavenger receptor class B member 1 isoform A.
    
 0.756
UBE2R2
Ubiquitin-conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.749
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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