STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNE2-1G1/S-specific cyclin-E2 isoform B; Belongs to the cyclin family. (410 aa)    
Predicted Functional Partners:
CDK2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.993
CDKN1A
Cyclin-dependent kinase inhibitor 1.
   
 0.986
ITM2B
Integral membrane protein 2B isoform B.
   
 0.984
RBL1
Retinoblastoma-like protein 1 isoform A.
   
 0.982
RBL2
Uncharacterized protein.
   
 0.982
CDKN1C
Cyclin-dependent kinase inhibitor 1C.
   
 0.977
SKP2
S-phase kinase-associated protein 2.
   
 0.977
CDKN1D
Cyclin-dependent kinase inhibitor 1D.
   
 0.977
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.976
CDC25A
M-phase inducer phosphatase 1.
   
 0.970
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.