STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P4HBProtein disulfide-isomerase. (512 aa)    
Predicted Functional Partners:
ERO1B-2
Uncharacterized protein.
   
 0.983
ERO1B
ERO1-like protein beta.
   
 0.980
HSPA5
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.910
CALR
Calreticulin.
   
 0.884
P4HA1
Prolyl 4-hydroxylase subunit alpha-1 isoform C.
   
 0.842
P4HA3
Prolyl 4-hydroxylase subunit alpha-3.
   
 0.839
MTTP
Microsomal triglyceride transfer protein large subunit.
    
 0.819
Y1Q_0022249
Uncharacterized protein.
   
 0.803
Y1Q_0022269
Vitellogenin domain-containing protein.
    
 0.792
ANKRD45
Ankyrin repeat domain-containing protein 45 isoform B.
   
 0.737
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.