STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDN1Endothelin-1. (200 aa)    
Predicted Functional Partners:
EDNRA
Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
Y1Q_0007371
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.994
EDN3
Endothelin-3.
     
0.960
EDN2
Endothelin-2.
     
0.954
AGTR2
Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.854
ECEL1L
Endothelin-converting enzyme-like 1 isoform B.
     
 0.829
ECE2-2
Uncharacterized protein.
     
 0.828
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
 0.758
NPSR1
Neuropeptide S receptor; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
    
 0.752
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.