MAP2K3 protein (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MAP2K3

Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)

Predicted Functional Partners:

MAPK14

0.984

MAPK11

0.984

MAP3K7

0.977

MAPK12

0.977

Y1Q_0020451

0.968

Y1Q_0013899

0.965

MAPK1

0.965

MAP3K5

0.963

MAP3K15

0.963

TAB1

0.953

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAP2K3	MAP3K15	A0A151N1R3	A0A151P1W9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 15 isoform C.	0.963
MAP2K3	MAP3K5	A0A151N1R3	A0A151M3J9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.963
MAP2K3	MAP3K7	A0A151N1R3	A0A151MTU0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 7 isoform A.	0.977
MAP2K3	MAPK1	A0A151N1R3	A0A151NRL4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.965
MAP2K3	MAPK11	A0A151N1R3	A0A151PFF4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.984
MAP2K3	MAPK12	A0A151N1R3	A0A151PEP0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.977
MAP2K3	MAPK14	A0A151N1R3	A0A151N8L6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.984
MAP2K3	TAB1	A0A151N1R3	A0A151NIG6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.	0.953
MAP2K3	Y1Q_0013899	A0A151N1R3	A0A151MP93	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.965
MAP2K3	Y1Q_0020451	A0A151N1R3	A0A151NTV5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.968
MAP3K15	MAP2K3	A0A151P1W9	A0A151N1R3	Mitogen-activated protein kinase kinase kinase 15 isoform C.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.963
MAP3K5	MAP2K3	A0A151M3J9	A0A151N1R3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.963
MAP3K7	MAP2K3	A0A151MTU0	A0A151N1R3	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.977
MAP3K7	MAPK1	A0A151MTU0	A0A151NRL4	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.922
MAP3K7	MAPK11	A0A151MTU0	A0A151PFF4	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Mitogen-activated protein kinase.	0.942
MAP3K7	MAPK12	A0A151MTU0	A0A151PEP0	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Mitogen-activated protein kinase.	0.940
MAP3K7	MAPK14	A0A151MTU0	A0A151N8L6	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Mitogen-activated protein kinase.	0.942
MAP3K7	TAB1	A0A151MTU0	A0A151NIG6	Mitogen-activated protein kinase kinase kinase 7 isoform A.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.	0.999
MAP3K7	Y1Q_0013899	A0A151MTU0	A0A151MP93	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Uncharacterized protein.	0.922
MAP3K7	Y1Q_0020451	A0A151MTU0	A0A151NTV5	Mitogen-activated protein kinase kinase kinase 7 isoform A.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.922