STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDHD1WD repeat and HMG-box DNA-binding protein 1. (1163 aa)    
Predicted Functional Partners:
POLA1
DNA polymerase.
   
 
 0.998
MCM4
DNA helicase; Belongs to the MCM family.
   
 
 0.997
CDC45
Cell division control 45-like protein.
   
 
 0.993
MCM5
DNA helicase; Belongs to the MCM family.
   
 
 0.990
GINS4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.989
MCM6
DNA helicase; Belongs to the MCM family.
   
 
 0.987
MCM2
DNA helicase; Belongs to the MCM family.
   
 
 0.987
GINS2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
 
 0.985
GINS3
DNA replication complex GINS protein PSF3.
   
 
 0.982
TIPIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.979
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.