STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX51ATP-dependent RNA helicase DDX51; Belongs to the DEAD box helicase family. (735 aa)    
Predicted Functional Partners:
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 0.794
EBNA1BP2
Putative rRNA-processing protein EBP2.
   
 0.724
DHX9
ATP-dependent RNA helicase A.
   
 0.696
NOP58
Nucleolar protein 58.
  
 
 0.680
SKIV2L2
Superkiller viralicidic activity 2-like 2.
   
 0.675
SF3B1
Splicing factor 3B subunit 1.
   
 0.670
RRP8
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
   
 
 0.663
EIF4A3-2
Uncharacterized protein; Belongs to the DEAD box helicase family.
  
0.658
UTP18
U3 small nucleolar RNA-associated 18-like protein.
   
 0.652
PSEN1-2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.651
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.