STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR2C1Uncharacterized protein. (661 aa)    
Predicted Functional Partners:
NRIP1
Nuclear receptor-interacting protein 1.
    
 0.690
FKBP10
Peptidylprolyl isomerase.
    
 0.632
NCOR1
Nuclear receptor corepressor 1 isoform B.
   
 0.626
Y1Q_0018673
Uncharacterized protein.
   
 0.626
HDAC3
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.589
RGR
RPE-retinal G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
     
 0.505
ZNF827
Zinc finger protein 827 isoform A.
    
 0.498
KCTD2
BTB/POZ domain-containing protein KCTD2.
    
 0.493
Y1Q_0017512
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.488
Y1Q_0017513
Mediator of RNA polymerase II transcription subunit 1-like.
    
  0.488
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.