STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3ESema domain-containing protein; Belongs to the semaphorin family. (774 aa)    
Predicted Functional Partners:
PLXND1-2
Sema domain-containing protein.
    
 0.947
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 0.815
PLXNA4
Sema domain-containing protein.
    
 0.724
PLXNA3
Sema domain-containing protein.
    
 0.717
PLXNC1
Plexin-C1.
    
0.704
NRP2-2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.684
PLXNA1
Sema domain-containing protein.
    
 0.671
MET
Hepatocyte growth factor receptor.
    
 0.637
MET-2
Uncharacterized protein.
    
 0.637
DOK4
Docking protein 4 isoform A.
      
 0.587
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.