STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3CUncharacterized protein; Belongs to the semaphorin family. (740 aa)    
Predicted Functional Partners:
NRP2
Neuropilin; Belongs to the neuropilin family.
  
 
 0.908
PLXND1-2
Sema domain-containing protein.
    
 0.846
NRP2-2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.792
MET
Hepatocyte growth factor receptor.
    
 0.637
MET-2
Uncharacterized protein.
    
 0.637
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
      
 0.519
EFNB2
Ephrin-B2; Belongs to the ephrin family.
   
  
 0.511
SLIT2
Slit-like protein 2 protein.
      
 0.504
PLXNA3
Sema domain-containing protein.
    
 0.494
PLXNA1
Sema domain-containing protein.
    
0.477
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.