STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKNOX1Homeobox protein PKNOX1 isoform A. (448 aa)    
Predicted Functional Partners:
PBX2
Pre-B-cell leukemia transcription factor 2 isoform A.
    
0.745
Y1Q_0005418
Homeobox domain-containing protein.
    
0.745
PBX3
Pre-B-cell leukemia transcription factor 3.
    
0.745
HOXB1
Homeobox protein Hox-B1.
   
 0.735
IL2RA
Interleukin-15 receptor subunit alpha isoform A.
      
 0.560
IL17RA
Interleukin-17 receptor A.
      
 0.537
CCR7
C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.
      
 0.461
HHEX
Hematopoietically-expressed homeobox protein HHEX.
   
 
 0.449
Y1Q_0009747
Mothers against decapentaplegic homolog.
    
 0.429
SMAD4
Mothers against decapentaplegic homolog.
    
 0.429
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.