STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKZF2LZinc finger protein Helios. (539 aa)    
Predicted Functional Partners:
RPS26
40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.
 
  
 0.689
WDR33
Pre-mRNA 3' end processing protein WDR33.
    
 0.683
DUSP28
Dual specificity phosphatase 28.
    
 
 0.673
DNAJC22
DnaJ-like protein subfamily C member 22 isoform A.
    
 0.673
ZC3H15
Zinc finger CCCH domain-containing protein 15.
      
 0.666
SLC9A8
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    
 0.666
LMBR1L
Protein LMBR1L.
      
 0.665
CRBN
Protein cereblon isoform B.
    
 
 0.601
METTL22
Methyltransferase-like protein 22 isoform D.
      
 0.590
IKZF1-1
DNA-binding protein Ikaros isoform B.
   
  
0.483
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.