STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRK5-2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (641 aa)    
Predicted Functional Partners:
ARRB2
Arrestin_C domain-containing protein.
   
 0.856
ARR3
Arrestin-C isoform B.
   
 0.856
RHO
Rhodopsin.
   
 0.731
RCVRN
Recoverin.
   
 0.711
CXCR1
C-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.707
CXCR4
C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.702
SMO
Smoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.600
GNB4
Guanine nucleotide-binding protein subunit beta-4.
   
 0.570
GNB3
WD_REPEATS_REGION domain-containing protein.
   
 0.570
PPAN
Suppressor of SWI4 1-like protein.
     
 0.550
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.