STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDM4BUncharacterized protein. (1031 aa)    
Predicted Functional Partners:
ZMPSTE24
CAAX prenyl protease 1-like protein.
   
 0.590
HIST1H4D
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.543
HIST2H3D
Histone H3; Belongs to the histone H3 family.
    
 0.534
Y1Q_0016504
Histone domain-containing protein.
    
 0.534
CENPA
Histone H3-like centromeric protein A.
    
 0.534
H3F3B
Histone H3; Belongs to the histone H3 family.
    
 0.534
Y1Q_0013172
Histone domain-containing protein.
    
 0.534
MYD88
Myeloid differentiation primary response protein MyD88.
    
 0.529
ATM
Non-specific serine/threonine protein kinase.
     
 0.510
RAD21
Double-strand-break repair rad21-like protein.
      
 0.501
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.