STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y1Q_0000266Uncharacterized protein. (595 aa)    
Predicted Functional Partners:
Y1Q_0000264
Transducin-like enhancer protein 2.
 
      0.900
AES
Amino-terminal enhancer of split.
 
      0.884
Y1Q_0000267
TLE_N domain-containing protein.
 
      0.882
HES1
Transcription factor HES-1.
    
 0.599
TCF7
Transcription factor 7 isoform A.
    
 0.572
LEF1
Lymphoid enhancer-binding factor 1 isoform B.
    
 0.572
TCF7L1
Transcription factor 7-like 1 isoform D.
    
 0.571
TCF7L2
Transcription factor 7-like 2 isoform A.
    
 0.571
GAK-2
Uncharacterized protein.
      
 0.538
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
    
 0.479
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.