STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEPHHephaestin isoform B; Belongs to the multicopper oxidase family. (1245 aa)    
Predicted Functional Partners:
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
    
 0.730
SLC36A1
Proton-coupled amino acid transporter 1 isoform A.
      
 0.674
FAT3A
Protocadherin Fat 3.
      
 0.670
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
    
 
 0.517
PEX10
Peroxisome biogenesis factor 10.
    
 
 0.498
PROS1-1
Vitamin K-dependent protein S isoform B.
   
 0.493
Y1Q_0007629
Uncharacterized protein.
  
 
 0.482
ATP7B-2
Uncharacterized protein.
  
 
 0.482
ATP7B
Copper-transporting ATPase 2.
  
 
 0.482
AASDH
Acyl-CoA synthetase family member 4 isoform A.
     
 0.479
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.