STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNMTPhenylethanolamine N-methyltransferase. (265 aa)    
Predicted Functional Partners:
DBH
Dopamine beta-hydroxylase.
   
 
 0.985
LRTOMT
Transmembrane O-methyltransferase.
     
 0.930
COMT
Catechol O-methyltransferase.
     
 0.929
MAOA
Amine oxidase.
     
 0.916
MAOB
Amine oxidase.
     
 0.916
TH
BH4_AAA_HYDROXYL_2 domain-containing protein.
      
 0.728
Y1Q_0013850
Uncharacterized protein; Belongs to the heat shock protein 70 family.
      
 0.663
PTH
Parathyroid hormone.
      
 0.591
HSF2BP
Heat shock factor 2-binding protein.
      
 0.559
PAH
Phenylalanine-4-hydroxylase isoform B.
      
 0.542
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.