STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBX21T-box transcription factor TBX21. (582 aa)    
Predicted Functional Partners:
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
  
 0.746
CD4
T-cell surface glycoprotein CD4.
   
  
 0.704
GATA3
Trans-acting T-cell-specific transcription factor GATA-3.
   
 
 0.645
KDM6B-2
Uncharacterized protein.
    
 
 0.590
HLX-1
H2.0-like homeobox protein isoform A.
    
 
 0.546
IL10
Interleukin-10.
   
  
 0.543
IL15-1
Interleukin; Belongs to the IL-15/IL-21 family.
      
 0.540
TGFB1
TGF_BETA_2 domain-containing protein.
     
 0.517
Y1Q_0005378
Uncharacterized protein.
   
  
 0.517
EOMES
Eomesodermin-like protein isoform B.
  
 
0.512
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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