STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y1Q_0016627Uncharacterized protein. (1154 aa)    
Predicted Functional Partners:
KMT2D-2
Uncharacterized protein.
 
     0.945
Y1Q_0003629
Histone-lysine N-methyltransferase 2D-like.
 
     
0.900
ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.872
RBBP5
Retinoblastoma-binding protein 5 isoform B.
    
 0.868
WDR5
WD repeat-containing protein 5.
   
 0.761
HIST1H4D
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.686
PRKAB1
5'-AMP-activated protein kinase subunit beta-1.
    
  0.647
KDM6B
Lysine-specific demethylase 6B isoform A.
   
 0.644
PRKAA1-2
Non-specific serine/threonine protein kinase.
   
  0.616
CENPN
Centromere protein N.
   
 0.610
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.