STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC8Histone deacetylase 8. (366 aa)    
Predicted Functional Partners:
LEO1
RNA polymerase-associated protein LEO1.
   
 0.934
ARID4A
AT-rich interactive domain-containing protein 4A isoform A.
   
 0.930
Y1Q_0014762
Tudor domain-containing protein.
   
 0.930
ARID4B
AT-rich interactive domain-containing protein 4B isoform B.
   
 0.930
SUDS3
Sin3 histone deacetylase corepressor complex component SDS3.
    
 0.861
ZMPSTE24
CAAX prenyl protease 1-like protein.
   
 0.820
RBBP4-2
WD_REPEATS_REGION domain-containing protein.
   
 0.799
RBBP4
Histone-binding protein RBBP4.
   
 0.799
Y1Q_0001537
HDAC_interact domain-containing protein.
   
 0.794
NWD1
Tetraspanin.
   
 0.794
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.