STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDI1Isopentenyl-diphosphate Delta-isomerase 1. (303 aa)    
Predicted Functional Partners:
FDPS
Farnesyl pyrophosphate synthase isoform B; Belongs to the FPP/GGPP synthase family.
  
 
 0.990
GGPS1
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.978
MVD
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 
 0.973
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.968
COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial.
  
 
 0.952
SQLE
Squalene monooxygenase.
   
  
 0.929
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
  
 0.908
Y1Q_0014975
Glutamate 5-kinase-like.
     
  0.906
CYP51A1
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
  
  
 0.903
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
 
  
 0.891
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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