STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6A-2Sema domain-containing protein; Belongs to the semaphorin family. (1040 aa)    
Predicted Functional Partners:
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 0.669
MET
Hepatocyte growth factor receptor.
    
 0.650
MET-2
Uncharacterized protein.
    
 0.639
PLXNC1
Plexin-C1.
    
 0.601
PLXND1-2
Sema domain-containing protein.
    
0.551
PLPP4
Phosphatidate phosphatase PPAPDC1A.
      
 0.529
PLXNA4
Sema domain-containing protein.
    
0.528
EPHA8
Uncharacterized protein.
   
 
 0.506
DCLK1
Serine/threonine-protein kinase DCLK1.
      
 0.484
PLXND1
Plexin-D1.
    
0.482
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.