STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP3BDNA topoisomerase III beta. (862 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
   
 0.999
WRN
WRN RecQ like helicase.
  
 0.998
TDRD3
Tudor domain containing 3.
    
 0.993
RMI1
RecQ mediated genome instability 1.
    
 0.989
RPA3
Replication protein A3.
    
 0.981
RPA1
Replication protein A1.
   
 0.974
BLM
BLM RecQ like helicase.
  
 0.973
RPA2
Replication protein A2.
    
 0.957
RMI2
RecQ mediated genome instability 2.
    
 0.953
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
    
 0.945
Your Current Organism:
Crocodylus porosus
NCBI taxonomy Id: 8502
Other names: Australian saltwater crocodile, C. porosus, ZMB 278, estuarine crocodile
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.