STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRAK4Interleukin 1 receptor associated kinase 4. (489 aa)    
Predicted Functional Partners:
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.998
IRAK2
Interleukin 1 receptor associated kinase 2.
   
0.993
TRAF6
TNF receptor associated factor 6.
   
 0.986
TIRAP
TIR domain containing adaptor protein.
    
 0.978
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.968
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
 
0.967
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.965
PELI1
Pellino E3 ubiquitin protein ligase 1.
    
 0.952
TICAM1
Toll like receptor adaptor molecule 1.
   
 0.943
MAVS
Mitochondrial antiviral signaling protein.
    
 0.937
Your Current Organism:
Crocodylus porosus
NCBI taxonomy Id: 8502
Other names: Australian saltwater crocodile, C. porosus, ZMB 278, estuarine crocodile
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.