STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FZD4Frizzled class receptor 4. (525 aa)    
Predicted Functional Partners:
LRP6
LDL receptor related protein 6.
    
 0.963
WNT11
Wnt family member 11.
    
 0.963
LRP5
LDL receptor related protein 5.
    
 0.962
WNT5A
Wnt family member 5A.
    
 0.959
WNT5B
Wnt family member 5B.
    
 0.955
NDP
Norrin cystine knot growth factor NDP.
    
 
 0.954
RYK
Receptor like tyrosine kinase.
    
 0.948
ROR1
Receptor tyrosine kinase like orphan receptor 1.
    
 0.947
ROR2
Receptor tyrosine kinase like orphan receptor 2.
    
 0.945
ENSCPRP00005011242
annotation not available
    
 0.939
Your Current Organism:
Crocodylus porosus
NCBI taxonomy Id: 8502
Other names: Australian saltwater crocodile, C. porosus, ZMB 278, estuarine crocodile
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.