STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N302_068473-hydroxyanthranilate 3,4-dioxygenase. (285 aa)    
Predicted Functional Partners:
N302_02274
Kynureninase.
  
 
 0.985
N302_02295
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.
  
 
 0.983
N302_08641
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
  0.936
N302_16344
Kynurenine 3-monooxygenase.
  
  
 0.847
N302_10550
Uncharacterized protein.
    
 0.721
N302_06773
Glutamate decarboxylase 1.
   
   0.671
N302_03456
Indoleamine 2,3-dioxygenase 2.
   
 
 0.670
N302_03873
Nicotinate-nucleotide pyrophosphorylase [carboxylating].
   
  
 0.655
TDO2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
   
  
 0.598
N302_08662
Glutamine-dependent NAD(+) synthetase.
      
 0.569
Your Current Organism:
Corvus brachyrhynchos
NCBI taxonomy Id: 85066
Other names: American crow, C. brachyrhynchos
Server load: low (24%) [ZH]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.