Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSP90B1Heat shock protein 90 beta family member 1. (796 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5.
  
 0.999
PDIA4
Protein disulfide isomerase family A member 4.
  
 0.996
CALR3
Calreticulin 3.
   
 0.994
CALR
Calreticulin.
   
 0.994
PDIA3
Protein disulfide isomerase family A member 3.
  
 0.994
TRAP1
TNF receptor associated protein 1.
  
0.992
PDIA6
Protein disulfide isomerase family A member 6.
  
 0.990
ENSSPUP00000009648
annotation not available
   
 0.989
P4HB
Prolyl 4-hydroxylase subunit beta.
  
 0.989
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
   
 0.988
Your Current Organism:
Sphenodon punctatus
NCBI taxonomy Id: 8508
Other names: Hatteria punctata, S. punctatus, hatteria, tuatara
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