STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNRF3Zinc and ring finger 3. (834 aa)    
Predicted Functional Partners:
RSPO1
R-spondin 1.
    
 0.996
RSPO2
R-spondin 2.
    
 0.985
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.983
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
    
 0.958
RSPO4
R-spondin 4.
    
 0.947
RSPO3
R-spondin 3.
    
 0.924
FZD6
Frizzled class receptor 6.
    
 0.921
FZD10
Frizzled class receptor 10.
    
 0.912
ENSSPUP00000006630
annotation not available
    
 0.909
FZD3
Frizzled class receptor 3.
    
 0.905
Your Current Organism:
Sphenodon punctatus
NCBI taxonomy Id: 8508
Other names: Hatteria punctata, S. punctatus, hatteria, tuatara
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.