Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
T45_00040Hypothetical protein. (77 aa)    
Predicted Functional Partners:
korA
2-oxoglutarate oxidoreductase subunit KorA.
    
 0.813
geoB_1
Geranial dehydrogenase; Belongs to the aldehyde dehydrogenase family.
       0.793
gloB_1
Hydroxyacylglutathione hydrolase.
       0.742
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
  0.735
accA
Acetyl-coenzyme A carboxylase carboxyl.
     
  0.732
mutB_2
methylmalonyl-CoA mutase large subunit.
     
 0.607
T45_01443
Putative peptidoglycan binding domain protein.
  
     0.599
acoA
Acetoin:2,6-dichlorophenolindophenol.
     
  0.594
T45_08389
Hypothetical protein.
  
     0.577
scpA_1
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
     
  0.575
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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