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query proteins and first shell of interactors
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second shell of interactors
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[Homology]
Score
guaA_1GMP synthase [glutamine-hydrolyzing]. (247 aa)    
Predicted Functional Partners:
guaB_5
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.970
guaB_6
Inosine-5'-monophosphate dehydrogenase.
  
 
 0.943
T45_07369
Putative oxidoreductase/MSMEI_1564.
  
 
 0.925
guaB_4
Inosine-5'-monophosphate dehydrogenase.
  
 
 0.889
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.889
hpt
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.888
guaA_2
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
 0.868
rdgB
DITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.858
nagD
Ribonucleotide monophosphatase NagD; Belongs to the HAD-like hydrolase superfamily.
    
  0.857
yhcR
Endonuclease YhcR precursor; Belongs to the 5'-nucleotidase family.
     
 0.851
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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