Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prtS_1Protease PrtS precursor; Extracellular zinc metalloprotease. (360 aa)    
Predicted Functional Partners:
T45_00499
Hypothetical protein.
       0.792
T45_00501
Multidrug efflux system protein MdtL.
       0.710
leuA_1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
       0.666
T45_00496
Tellurite resistance protein TerB.
       0.611
lieA_2
Leupeptin-inactivating enzyme 1 precursor.
 
 
 0.501
xynAS9_1
Endo-1,4-beta-xylanase A precursor.
   
  
 0.483
bglA_1
Beta-glucosidase.
       0.482
T45_04994
Thermophilic serine proteinase precursor.
      
 0.468
T45_00705
Hypothetical protein.
  
     0.413
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (30%) [HD]