T45_00520 protein (Streptomyces turgidiscabies)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

T45_00520

HIT-like protein. (120 aa)

Predicted Functional Partners:

rnz_1

0.798

add_3

0.778

ybeY

0.717

kdgK_1

0.712

ybeZ_1

0.629

corC_1

0.627

dnaJ_1

0.605

puuA

0.539

glnA_1

0.539

glnA_2

0.539

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_00520	add_3	T45_00520	T45_00518	HIT-like protein.	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	0.778
T45_00520	corC_1	T45_00520	T45_00514	HIT-like protein.	Magnesium and cobalt efflux protein CorC.	0.627
T45_00520	dnaJ_1	T45_00520	T45_00531	HIT-like protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.605
T45_00520	glnA_1	T45_00520	T45_03345	HIT-like protein.	Putative glutamine synthetase 2.	0.539
T45_00520	glnA_2	T45_00520	T45_03700	HIT-like protein.	Glutamine synthetase.	0.539
T45_00520	kdgK_1	T45_00520	T45_00517	HIT-like protein.	2-dehydro-3-deoxygluconokinase.	0.712
T45_00520	puuA	T45_00520	T45_00344	HIT-like protein.	Gamma-glutamylputrescine synthetase PuuA; Belongs to the glutamine synthetase family.	0.539
T45_00520	rnz_1	T45_00520	T45_00519	HIT-like protein.	Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.	0.798
T45_00520	ybeY	T45_00520	T45_00515	HIT-like protein.	Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.717
T45_00520	ybeZ_1	T45_00520	T45_00516	HIT-like protein.	PhoH-like protein.	0.629
add_3	T45_00520	T45_00518	T45_00520	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	HIT-like protein.	0.778
add_3	corC_1	T45_00518	T45_00514	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	Magnesium and cobalt efflux protein CorC.	0.441
add_3	dnaJ_1	T45_00518	T45_00531	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.519
add_3	kdgK_1	T45_00518	T45_00517	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	2-dehydro-3-deoxygluconokinase.	0.804
add_3	rnz_1	T45_00518	T45_00519	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.	0.847
add_3	ybeY	T45_00518	T45_00515	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.442
add_3	ybeZ_1	T45_00518	T45_00516	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	PhoH-like protein.	0.534
corC_1	T45_00520	T45_00514	T45_00520	Magnesium and cobalt efflux protein CorC.	HIT-like protein.	0.627
corC_1	add_3	T45_00514	T45_00518	Magnesium and cobalt efflux protein CorC.	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.	0.441
corC_1	kdgK_1	T45_00514	T45_00517	Magnesium and cobalt efflux protein CorC.	2-dehydro-3-deoxygluconokinase.	0.725