T45_00536 protein (Streptomyces turgidiscabies)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

T45_00536

Stage II sporulation protein E (SpoIIE). (714 aa)

Predicted Functional Partners:

luxQ

0.933

barA_2

0.853

afsQ1_1

0.831

T45_09072

0.814

rsbP_1

0.813

rsbV_1

0.806

rsbP_2

0.772

rsbU_5

0.769

T45_03328

0.768

hemN_1

0.753

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_00536	T45_03328	T45_00536	T45_03328	Stage II sporulation protein E (SpoIIE).	Stage II sporulation protein E (SpoIIE).	0.768
T45_00536	T45_09072	T45_00536	T45_09072	Stage II sporulation protein E (SpoIIE).	Sensory histidine kinase AtoS.	0.814
T45_00536	afsQ1_1	T45_00536	T45_00538	Stage II sporulation protein E (SpoIIE).	Transcriptional regulatory protein AfsQ1.	0.831
T45_00536	barA_2	T45_00536	T45_05328	Stage II sporulation protein E (SpoIIE).	Signal transduction histidine-protein kinase.	0.853
T45_00536	hemN_1	T45_00536	T45_00535	Stage II sporulation protein E (SpoIIE).	Oxygen-independent coproporphyrinogen-III oxidase 1; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.	0.753
T45_00536	luxQ	T45_00536	T45_00537	Stage II sporulation protein E (SpoIIE).	Autoinducer 2 sensor kinase/phosphatase LuxQ.	0.933
T45_00536	rsbP_1	T45_00536	T45_00823	Stage II sporulation protein E (SpoIIE).	Phosphoserine phosphatase RsbP.	0.813
T45_00536	rsbP_2	T45_00536	T45_01376	Stage II sporulation protein E (SpoIIE).	Phosphoserine phosphatase RsbP.	0.772
T45_00536	rsbU_5	T45_00536	T45_03109	Stage II sporulation protein E (SpoIIE).	Phosphoserine phosphatase RsbU.	0.769
T45_00536	rsbV_1	T45_00536	T45_00757	Stage II sporulation protein E (SpoIIE).	anti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family.	0.806
T45_03328	T45_00536	T45_03328	T45_00536	Stage II sporulation protein E (SpoIIE).	Stage II sporulation protein E (SpoIIE).	0.768
T45_03328	T45_09072	T45_03328	T45_09072	Stage II sporulation protein E (SpoIIE).	Sensory histidine kinase AtoS.	0.826
T45_03328	barA_2	T45_03328	T45_05328	Stage II sporulation protein E (SpoIIE).	Signal transduction histidine-protein kinase.	0.853
T45_03328	luxQ	T45_03328	T45_00537	Stage II sporulation protein E (SpoIIE).	Autoinducer 2 sensor kinase/phosphatase LuxQ.	0.743
T45_03328	rsbP_1	T45_03328	T45_00823	Stage II sporulation protein E (SpoIIE).	Phosphoserine phosphatase RsbP.	0.464
T45_03328	rsbP_2	T45_03328	T45_01376	Stage II sporulation protein E (SpoIIE).	Phosphoserine phosphatase RsbP.	0.757
T45_03328	rsbV_1	T45_03328	T45_00757	Stage II sporulation protein E (SpoIIE).	anti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family.	0.693
T45_09072	T45_00536	T45_09072	T45_00536	Sensory histidine kinase AtoS.	Stage II sporulation protein E (SpoIIE).	0.814
T45_09072	T45_03328	T45_09072	T45_03328	Sensory histidine kinase AtoS.	Stage II sporulation protein E (SpoIIE).	0.826
T45_09072	afsQ1_1	T45_09072	T45_00538	Sensory histidine kinase AtoS.	Transcriptional regulatory protein AfsQ1.	0.757