Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aprX_1Serine protease AprX; Belongs to the peptidase S8 family. (1107 aa)    
Predicted Functional Partners:
T45_00634
RNA pyrophosphohydrolase; Belongs to the Nudix hydrolase family.
 
     0.730
cpt
Carboxypeptidase T precursor.
  
 0.727
lieA_2
Leupeptin-inactivating enzyme 1 precursor.
 
  
 0.684
T45_00633
Hypothetical protein.
 
     0.678
T45_00631
Hypothetical protein.
 
     0.640
pepN_2
Aminopeptidase N.
    
  0.560
T45_03628
Hypothetical protein.
 
   0.534
pepN_1
Aminopeptidase N.
    
  0.514
pknB_6
Serine/threonine-protein kinase PknB.
  
 
   0.476
T45_03481
Hypothetical protein.
  
     0.472
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (30%) [HD]