Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gcvT_1Aminomethyltransferase; Belongs to the GcvT family. (1128 aa)    
Predicted Functional Partners:
T45_00709
Sarcosine oxidase, gamma subunit family.
 0.998
soxB
Sarcosine oxidase subunit beta.
 
  
  0.994
mlr_1
4-methylaminobutanoate oxidase; Belongs to the GcvT family.
 
0.984
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.893
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
    
 0.854
T45_05634
D-amino acid dehydrogenase small subunit.
     
  0.850
strB1
Inosamine-phosphate amidinotransferase 1.
     
  0.850
ltaE_1
Low specificity L-threonine aldolase.
     
  0.850
gltB_1
Glutamate synthase [NADPH] large chain.
  
 
 0.848
gcvT_2
Aminomethyltransferase; Belongs to the GcvT family.
 
 0.775
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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