gcvT_1 protein (Streptomyces turgidiscabies)

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Score

gcvT_1

Aminomethyltransferase; Belongs to the GcvT family. (1128 aa)

Predicted Functional Partners:

T45_00709

0.999

soxB

0.996

mlr_1

0.990

mlr_2

0.928

gcvP

0.927

kbl

0.895

ltaE_1

0.891

gltB_1

0.877

hcnC_1

0.848

glyA_1

0.811

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_00709	gcvP	T45_00709	T45_09295	Sarcosine oxidase, gamma subunit family.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.908
T45_00709	gcvT_1	T45_00709	T45_00710	Sarcosine oxidase, gamma subunit family.	Aminomethyltransferase; Belongs to the GcvT family.	0.999
T45_00709	gltB_1	T45_00709	T45_04042	Sarcosine oxidase, gamma subunit family.	Glutamate synthase [NADPH] large chain.	0.912
T45_00709	glyA_1	T45_00709	T45_01469	Sarcosine oxidase, gamma subunit family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.823
T45_00709	hcnC_1	T45_00709	T45_02830	Sarcosine oxidase, gamma subunit family.	Hydrogen cyanide synthase subunit HcnC precursor.	0.988
T45_00709	ltaE_1	T45_00709	T45_06747	Sarcosine oxidase, gamma subunit family.	Low specificity L-threonine aldolase.	0.891
T45_00709	mlr_1	T45_00709	T45_00712	Sarcosine oxidase, gamma subunit family.	4-methylaminobutanoate oxidase; Belongs to the GcvT family.	0.999
T45_00709	mlr_2	T45_00709	T45_08842	Sarcosine oxidase, gamma subunit family.	4-methylaminobutanoate oxidase.	0.994
T45_00709	soxB	T45_00709	T45_00711	Sarcosine oxidase, gamma subunit family.	Sarcosine oxidase subunit beta.	0.999
gcvP	T45_00709	T45_09295	T45_00709	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Sarcosine oxidase, gamma subunit family.	0.908
gcvP	gcvT_1	T45_09295	T45_00710	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Aminomethyltransferase; Belongs to the GcvT family.	0.927
gcvP	gltB_1	T45_09295	T45_04042	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Glutamate synthase [NADPH] large chain.	0.999
gcvP	glyA_1	T45_09295	T45_01469	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.993
gcvP	hcnC_1	T45_09295	T45_02830	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Hydrogen cyanide synthase subunit HcnC precursor.	0.841
gcvP	kbl	T45_09295	T45_05567	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.	0.955
gcvP	ltaE_1	T45_09295	T45_06747	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Low specificity L-threonine aldolase.	0.953
gcvP	mlr_1	T45_09295	T45_00712	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	4-methylaminobutanoate oxidase; Belongs to the GcvT family.	0.998
gcvP	mlr_2	T45_09295	T45_08842	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	4-methylaminobutanoate oxidase.	0.908
gcvP	soxB	T45_09295	T45_00711	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	Sarcosine oxidase subunit beta.	0.908
gcvT_1	T45_00709	T45_00710	T45_00709	Aminomethyltransferase; Belongs to the GcvT family.	Sarcosine oxidase, gamma subunit family.	0.999