| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acsA_1 | adhE | T45_00771 | T45_02839 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.877 |
| acsA_1 | betB_1 | T45_00771 | T45_01555 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | NAD/NADP-dependent betaine aldehyde. | 0.744 |
| acsA_1 | dhbF_8 | T45_00771 | T45_05484 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Dimodular nonribosomal peptide synthase. | 0.862 |
| acsA_1 | fas6_1 | T45_00771 | T45_03755 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | LOG family protein ORF6 in fasciation locus. | 0.731 |
| acsA_1 | gbsA_1 | T45_00771 | T45_00716 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.829 |
| acsA_1 | gltB_1 | T45_00771 | T45_04042 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Glutamate synthase [NADPH] large chain. | 0.490 |
| adhE | acsA_1 | T45_02839 | T45_00771 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.877 |
| adhE | betB_1 | T45_02839 | T45_01555 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | NAD/NADP-dependent betaine aldehyde. | 0.717 |
| adhE | cmdD_1 | T45_02839 | T45_02353 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Chondramide synthase cmdD. | 0.851 |
| adhE | dhbF_8 | T45_02839 | T45_05484 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Dimodular nonribosomal peptide synthase. | 0.903 |
| adhE | fas6_1 | T45_02839 | T45_03755 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | LOG family protein ORF6 in fasciation locus. | 0.872 |
| adhE | gbsA_1 | T45_02839 | T45_00716 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.834 |
| adhE | gltB_1 | T45_02839 | T45_04042 | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glutamate synthase [NADPH] large chain. | 0.951 |
| betB_1 | acsA_1 | T45_01555 | T45_00771 | NAD/NADP-dependent betaine aldehyde. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.744 |
| betB_1 | adhE | T45_01555 | T45_02839 | NAD/NADP-dependent betaine aldehyde. | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.717 |
| betB_1 | cmdD_1 | T45_01555 | T45_02353 | NAD/NADP-dependent betaine aldehyde. | Chondramide synthase cmdD. | 0.769 |
| betB_1 | dhbF_8 | T45_01555 | T45_05484 | NAD/NADP-dependent betaine aldehyde. | Dimodular nonribosomal peptide synthase. | 0.841 |
| betB_1 | fas6_1 | T45_01555 | T45_03755 | NAD/NADP-dependent betaine aldehyde. | LOG family protein ORF6 in fasciation locus. | 0.751 |
| betB_1 | gbsA_1 | T45_01555 | T45_00716 | NAD/NADP-dependent betaine aldehyde. | Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.828 |
| betB_1 | gltB_1 | T45_01555 | T45_04042 | NAD/NADP-dependent betaine aldehyde. | Glutamate synthase [NADPH] large chain. | 0.841 |