| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| T45_00775 | T45_00776 | T45_00775 | T45_00776 | Serine protease. | Putative NUDIX hydrolase. | 0.902 |
| T45_00775 | arc | T45_00775 | T45_03386 | Serine protease. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.712 |
| T45_00775 | ftsH_1 | T45_00775 | T45_01398 | Serine protease. | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | 0.712 |
| T45_00775 | glpK_1 | T45_00775 | T45_03403 | Serine protease. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.680 |
| T45_00775 | glpK_2 | T45_00775 | T45_08126 | Serine protease. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.680 |
| T45_00775 | glpK_3 | T45_00775 | T45_08448 | Serine protease. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.680 |
| T45_00775 | lppS_9 | T45_00775 | T45_08736 | Serine protease. | Putative L,D-transpeptidase LppS precursor. | 0.681 |
| T45_00775 | pdg | T45_00775 | T45_00777 | Serine protease. | Ultraviolet N-glycosylase/AP lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.773 |
| T45_00775 | secD_2 | T45_00775 | T45_00999 | Serine protease. | Bifunctional preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.700 |
| T45_00775 | yrrB | T45_00775 | T45_02246 | Serine protease. | TPR repeat-containing protein YrrB. | 0.799 |
| T45_00776 | T45_00775 | T45_00776 | T45_00775 | Putative NUDIX hydrolase. | Serine protease. | 0.902 |
| T45_00776 | pdg | T45_00776 | T45_00777 | Putative NUDIX hydrolase. | Ultraviolet N-glycosylase/AP lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.763 |
| T45_00776 | yrrB | T45_00776 | T45_02246 | Putative NUDIX hydrolase. | TPR repeat-containing protein YrrB. | 0.474 |
| arc | T45_00775 | T45_03386 | T45_00775 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Serine protease. | 0.712 |
| arc | glpK_1 | T45_03386 | T45_03403 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
| arc | glpK_2 | T45_03386 | T45_08126 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
| arc | glpK_3 | T45_03386 | T45_08448 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.831 |
| arc | yrrB | T45_03386 | T45_02246 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | TPR repeat-containing protein YrrB. | 0.872 |
| ftsH_1 | T45_00775 | T45_01398 | T45_00775 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Serine protease. | 0.712 |
| ftsH_1 | glpK_1 | T45_01398 | T45_03403 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
