Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pel_1Pectate lyase precursor. (448 aa)    
Predicted Functional Partners:
pelA_1
Pectate lyase A precursor.
  
  
 0.892
pelA_3
Pectate lyase A precursor.
  
  
 0.892
pemA_3
Pectinesterase A precursor.
  
 0.885
pemA_2
Pectinesterase A precursor.
  
 0.879
pelX
Pectate disaccharide-lyase precursor.
 
  
  0.837
pelA_2
Pectate trisaccharide-lyase precursor.
 
  
0.823
pelE
Pectate lyase E precursor.
 
  
 
0.810
pemA_1
Pectinesterase A precursor.
 
  
0.718
manA_1
Mannan endo-1,4-beta-mannosidase precursor.
  
     0.680
T45_09274
Hypothetical protein.
 
     0.680
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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