close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T45_01309Transcriptional regulator PadR-like family protein. (228 aa)    
Predicted Functional Partners:
T45_01307
2-acyl-glycerophospho-ethanolamine acyltransferase.
 
   
 0.942
ino1_1
Inositol-3-phosphate synthase.
 
   
 0.923
T45_01311
Hypothetical protein.
       0.637
T45_08398
Hypothetical protein.
  
     0.636
T45_01306
Hypothetical protein.
  
  
 0.513
T45_06150
Major Facilitator Superfamily protein.
  
     0.497
T45_07443
Hypothetical protein.
  
     0.492
whiB7
Putative transcriptional regulator WhiB7; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.487
glnD
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
  
     0.487
T45_08396
Phosphatidylinositol mannoside acyltransferase.
  
     0.477
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (40%) [HD]