T45_01379 protein (Streptomyces turgidiscabies)

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Score

T45_01379

SEC-C motif protein. (321 aa)

Predicted Functional Partners:

secD_2

0.780

T45_01380

0.736

ubiE_4

0.654

glpQ1_1

0.639

secY

0.584

T45_06305

0.583

leuS

0.567

secE

0.557

ffh

0.543

secG

0.499

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_01379	T45_01380	T45_01379	T45_01380	SEC-C motif protein.	Hypothetical protein.	0.736
T45_01379	T45_06305	T45_01379	T45_06305	SEC-C motif protein.	Sensory histidine kinase AtoS.	0.583
T45_01379	ffh	T45_01379	T45_05784	SEC-C motif protein.	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.543
T45_01379	glpQ1_1	T45_01379	T45_01381	SEC-C motif protein.	Putative glycerophosphoryl diester.	0.639
T45_01379	leuS	T45_01379	T45_00549	SEC-C motif protein.	leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.567
T45_01379	secD_2	T45_01379	T45_00999	SEC-C motif protein.	Bifunctional preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.	0.780
T45_01379	secE	T45_01379	T45_07186	SEC-C motif protein.	Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.	0.557
T45_01379	secG	T45_01379	T45_04149	SEC-C motif protein.	Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.499
T45_01379	secY	T45_01379	T45_04391	SEC-C motif protein.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.584
T45_01379	ubiE_4	T45_01379	T45_04079	SEC-C motif protein.	Ubiquinone/menaquinone biosynthesis methyltransferase.	0.654
T45_01380	T45_01379	T45_01380	T45_01379	Hypothetical protein.	SEC-C motif protein.	0.736
T45_01380	glpQ1_1	T45_01380	T45_01381	Hypothetical protein.	Putative glycerophosphoryl diester.	0.700
T45_06305	T45_01379	T45_06305	T45_01379	Sensory histidine kinase AtoS.	SEC-C motif protein.	0.583
T45_06305	ubiE_4	T45_06305	T45_04079	Sensory histidine kinase AtoS.	Ubiquinone/menaquinone biosynthesis methyltransferase.	0.488
ffh	T45_01379	T45_05784	T45_01379	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	SEC-C motif protein.	0.543
ffh	secD_2	T45_05784	T45_00999	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	Bifunctional preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.	0.923
ffh	secE	T45_05784	T45_07186	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.	0.939
ffh	secG	T45_05784	T45_04149	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.929
ffh	secY	T45_05784	T45_04391	Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.949
glpQ1_1	T45_01379	T45_01381	T45_01379	Putative glycerophosphoryl diester.	SEC-C motif protein.	0.639