| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| arc | degP | T45_03386 | T45_06001 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Periplasmic serine endoprotease DegP precursor. | 0.712 |
| arc | glpK_1 | T45_03386 | T45_03403 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
| arc | glpK_2 | T45_03386 | T45_08126 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
| arc | glpK_3 | T45_03386 | T45_08448 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.831 |
| arc | htrA_1 | T45_03386 | T45_01382 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Putative serine protease HtrA. | 0.712 |
| arc | yrrB | T45_03386 | T45_02246 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | TPR repeat-containing protein YrrB. | 0.872 |
| degP | arc | T45_06001 | T45_03386 | Periplasmic serine endoprotease DegP precursor. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.712 |
| degP | ftsH_1 | T45_06001 | T45_01398 | Periplasmic serine endoprotease DegP precursor. | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | 0.712 |
| degP | glpK_1 | T45_06001 | T45_03403 | Periplasmic serine endoprotease DegP precursor. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.680 |
| degP | glpK_2 | T45_06001 | T45_08126 | Periplasmic serine endoprotease DegP precursor. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.680 |
| degP | glpK_3 | T45_06001 | T45_08448 | Periplasmic serine endoprotease DegP precursor. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.680 |
| degP | htrA_1 | T45_06001 | T45_01382 | Periplasmic serine endoprotease DegP precursor. | Putative serine protease HtrA. | 0.817 |
| degP | rplK | T45_06001 | T45_07184 | Periplasmic serine endoprotease DegP precursor. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.647 |
| degP | rplT | T45_06001 | T45_03333 | Periplasmic serine endoprotease DegP precursor. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.674 |
| degP | secD_2 | T45_06001 | T45_00999 | Periplasmic serine endoprotease DegP precursor. | Bifunctional preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.700 |
| degP | yrrB | T45_06001 | T45_02246 | Periplasmic serine endoprotease DegP precursor. | TPR repeat-containing protein YrrB. | 0.799 |
| ftsH_1 | degP | T45_01398 | T45_06001 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Periplasmic serine endoprotease DegP precursor. | 0.712 |
| ftsH_1 | glpK_1 | T45_01398 | T45_03403 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
| ftsH_1 | glpK_2 | T45_01398 | T45_08126 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.831 |
| ftsH_1 | glpK_3 | T45_01398 | T45_08448 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.831 |