nudF_1 protein (Streptomyces turgidiscabies)

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Score

nudF_1

ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (177 aa)

Predicted Functional Partners:

prs

0.838

nudF_3

0.683

metH

0.658

fumA

0.615

nadE

0.599

korA

0.539

T45_09072

0.497

guaA_2

0.477

rsbU_3

0.438

guaB_5

0.435

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_09072	guaA_2	T45_09072	T45_07354	Sensory histidine kinase AtoS.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.792
T45_09072	guaB_5	T45_09072	T45_07370	Sensory histidine kinase AtoS.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.575
T45_09072	metH	T45_09072	T45_03400	Sensory histidine kinase AtoS.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.860
T45_09072	nadE	T45_09072	T45_06531	Sensory histidine kinase AtoS.	Glutamine-dependent NAD(+)synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.509
T45_09072	nudF_1	T45_09072	T45_01397	Sensory histidine kinase AtoS.	ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.497
T45_09072	nudF_3	T45_09072	T45_03584	Sensory histidine kinase AtoS.	ADP-ribose pyrophosphatase.	0.815
T45_09072	prs	T45_09072	T45_02481	Sensory histidine kinase AtoS.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.782
T45_09072	rsbU_3	T45_09072	T45_01727	Sensory histidine kinase AtoS.	Phosphoserine phosphatase RsbU.	0.993
fumA	korA	T45_01693	T45_07222	Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	2-oxoglutarate oxidoreductase subunit KorA.	0.933
fumA	metH	T45_01693	T45_03400	Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.418
fumA	nadE	T45_01693	T45_06531	Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Glutamine-dependent NAD(+)synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.819
fumA	nudF_1	T45_01693	T45_01397	Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.615
guaA_2	T45_09072	T45_07354	T45_09072	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Sensory histidine kinase AtoS.	0.792
guaA_2	guaB_5	T45_07354	T45_07370	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA_2	metH	T45_07354	T45_03400	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.725
guaA_2	nadE	T45_07354	T45_06531	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamine-dependent NAD(+)synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.873
guaA_2	nudF_1	T45_07354	T45_01397	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.	0.477
guaA_2	prs	T45_07354	T45_02481	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.887
guaA_2	rsbU_3	T45_07354	T45_01727	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Phosphoserine phosphatase RsbU.	0.776
guaB_5	T45_09072	T45_07370	T45_09072	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Sensory histidine kinase AtoS.	0.575