Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lpdANAD(P)H dehydrogenase. (482 aa)    
Predicted Functional Partners:
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
 
 0.993
acoA
Acetoin:2,6-dichlorophenolindophenol.
 
 0.985
dlaT
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.962
bkdC
Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex.
 
 0.945
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.943
bkdB_3
3-methyl-2-oxobutanoate dehydrogenase subunit; Belongs to the 2-oxoacid dehydrogenase family.
 
 0.938
bkdB_2
3-methyl-2-oxobutanoate dehydrogenase subunit.
 
 0.930
bkdB_1
3-methyl-2-oxobutanoate dehydrogenase subunit.
 
 0.928
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.923
gltB_1
Glutamate synthase [NADPH] large chain.
    
 0.887
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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