typA protein (Streptomyces turgidiscabies) - STRING interaction network

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Score

typA

GTP-binding protein TypA/BipA. (635 aa)

Predicted Functional Partners:

guaA_2

0.793

T45_01735

0.757

rpsI

0.753

rplA

0.709

gltB_1

0.708

tig

0.693

rpmI

0.680

infC

0.667

rhlE_5

0.666

rpoB_1

0.645

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_01735	typA	T45_01735	T45_01736	Putative monoacyl phosphatidylinositol.	GTP-binding protein TypA/BipA.	0.757
gltB_1	guaA_2	T45_04042	T45_07354	Glutamate synthase [NADPH] large chain.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.986
gltB_1	rpoB_1	T45_04042	T45_07178	Glutamate synthase [NADPH] large chain.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.618
gltB_1	typA	T45_04042	T45_01736	Glutamate synthase [NADPH] large chain.	GTP-binding protein TypA/BipA.	0.708
guaA_2	gltB_1	T45_07354	T45_04042	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glutamate synthase [NADPH] large chain.	0.986
guaA_2	infC	T45_07354	T45_03335	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.625
guaA_2	rhlE_5	T45_07354	T45_08679	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	ATP-dependent RNA helicase RhlE.	0.407
guaA_2	rplA	T45_07354	T45_07183	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.952
guaA_2	rpmI	T45_07354	T45_03334	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.518
guaA_2	rpoB_1	T45_07354	T45_07178	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.939
guaA_2	rpsI	T45_07354	T45_04378	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.740
guaA_2	tig	T45_07354	T45_00608	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.771
guaA_2	typA	T45_07354	T45_01736	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein TypA/BipA.	0.793
infC	guaA_2	T45_03335	T45_07354	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.625
infC	rplA	T45_03335	T45_07183	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.965
infC	rpmI	T45_03335	T45_03334	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.986
infC	rpoB_1	T45_03335	T45_07178	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.759
infC	rpsI	T45_03335	T45_04378	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.967
infC	tig	T45_03335	T45_00608	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.751
infC	typA	T45_03335	T45_01736	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GTP-binding protein TypA/BipA.	0.667