Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
T45_01893(2E,6E)-farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (413 aa)    
Predicted Functional Partners:
crtB_2
All-trans-phytoene synthase.
  
 0.953
cyc2
Germacradienol/geosmin synthase.
 
  
 0.951
uppS_2
(2Z,6E)-farnesyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.945
uppS_1
Trans,polycis-polyprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.938
crtB_1
All-trans-phytoene synthase.
  
 0.916
mmpI_1
Major membrane protein I.
 
     0.904
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.891
cyc1
Epi-isozizaene synthase.
  
  
 0.881
T45_03629
(2E,6E)-farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
0.871
T45_05613
(2E,6E)-farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 
0.867
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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