Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
T45_01958phosphatase/MT3486. (155 aa)    
Predicted Functional Partners:
ribD2_2
2,5-diamino-6-ribosylamino-4(3H-pyrimidinone.
    
 0.887
ribF
Riboflavin biosynthesis protein RibF; Belongs to the ribF family.
  
 
 0.867
ssuE
FMN reductase (NADPH).
  
 
  0.852
T45_06592
NAD(P)H-dependent FAD/FMN reductase.
  
 
  0.852
ribE
Riboflavin synthase.
   
 
  0.852
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.851
guaB_5
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.796
guaA_2
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
 0.772
ribD2_1
2,5-diamino-6-ribosylamino-4(3H-pyrimidinone.
    
 0.764
bsr
blasticidin-S deaminase.
     
  0.732
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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