Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
arlS_1Signal transduction histidine-protein kinase. (470 aa)    
Predicted Functional Partners:
barA_2
Signal transduction histidine-protein kinase.
   
 0.986
copR
Transcriptional activator protein CopR.
 
  0.976
luxQ
Autoinducer 2 sensor kinase/phosphatase LuxQ.
   
 0.960
T45_09072
Sensory histidine kinase AtoS.
   
 0.876
mprA_1
Response regulator MprA.
  
  0.811
arlR
Response regulator ArlR.
  
  0.804
mprA_4
Response regulator MprA.
  
  0.803
yycF_2
Transcriptional regulatory protein YycF.
  
  0.803
tcrX_1
Putative transcriptional regulatory protein.
  
  0.802
tcrX_2
Putative transcriptional regulatory protein.
  
  0.802
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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