Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T45_02111Hypothetical protein. (270 aa)    
Predicted Functional Partners:
T45_09166
CHAT domain protein.
  
     0.673
nhaA
Na(+)/ H(+) antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.571
otsB
Trehalose-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.571
T45_04720
poly(beta-D-mannuronate lyase.
  
     0.570
T45_00395
Hypothetical protein.
   
   0.560
T45_00396
Hypothetical protein.
   
   0.560
rdgB
DITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.560
celS_1
Endoglucanase S precursor; Belongs to the glycosyl hydrolase 12 (cellulase H) family.
  
     0.553
tpc
2-methylisoborneol synthase.
  
     0.549
bga_4
Beta-galactosidase precursor; Belongs to the glycosyl hydrolase 35 family.
  
     0.541
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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